毕业论文:高血压联合用药分析
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摘 要
目的 利用合理用药监测系统(presciption automatic screening system,PASS.四川美康医药软件公司)对高血压病治疗中的用药状况进行监测,分析不合理联合用药实例,并对不同药物联合用药进行分析,以提高高血压病治疗的合理用药水平。
方法 登陆PASS临床药学工作站,对高血压病住院病人的用药医嘱连续监测两个月(2008年3月1日~4月30日)。获取联合用药的有问题医嘱(不合理联合用药)资料,经归纳、整理,按联合用药存在问题的性质(禁忌联用、不推荐联用、谨慎联用和关注联用)分类叙述。分析现在合理的联合用药。
结果 共监测用药医嘱6784条,监测出问题医嘱2317条,其中存在配伍禁忌1条;存在不同程度药物相互作用115条:其中不推荐联用28条,谨慎联用72条,关注联用15条。在目前常用的4类药物(利尿剂、β受体阻断药、二氢吡啶类钙拮抗药和ACEI药)中,并对四类的两两联合进行分析。
结论 PASS系统数据库中将药物相互作用的严重程度分为4个级别并配以相应的颜色警示:禁忌联用(黑色)、不推荐联用(红色)、谨
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and concern with the use) classification describes . Analysis is a reasonable combination.
Results: Directed a total of 6,784 drug monitoring, monitoring the problem directed 2317, of which there Incompatibility 1; varying degrees of drug interaction 115: which does not recommend the use 28, with 72 of caution, concerned about the use 15 . In the current four types of commonly used drugs (diuretics, β receptor blocker drugs, Dihydropyridine calcium antagonist drugs and ACEI), and four groups of the joint analysis of February 2.
Conclusion: PASS system database will be the e*tent of drug interactions into four levels and supported by the appropriate color warning: use of the taboo (Black), not recommended by the (red), combined with caution and concern with the (yellow), This classification for discussion. With the taboo: that the two drugs should be banned under any circumstances, shall not be granted the same patients, the warning light is black. Serious (not recommended combined): already clear that the adverse drug interactions, potentially dangerous, the warning light is red. Medium (combined with caution): assessment of each patient takes the risk of interaction, when necessary, for the yellow warning light. ONGOING (combined with concerns): gravity has not yet been determined, should assess the e*tent of the harm to the patients, when necessary, also in yellow warning light.
Key words: Hypertension; combined
目 录
正文……………………………………………………………………………………1
前言…………………………………………………………………………………1
资料与方法…………………………………………………………………………1
结果…………………………………………………………………………………2
不合理用药分析……………………………………………………………………3
不同药物联合使用分析……………………………………………………………6
参考文献………………………………………………………………………………8
综述…………………………………………………… ……………………………11
致谢…………………………………………………………………………… ……13
[正文]
高血压联合用药分析
学生:梁东菊 指导教师:刘卫、孙迪清、张兆芹
(泰山医学院药学院2004级中药学本科班,泰安271000)
1前言
《高血压治疗指南2000年版(JSH2000)》将收缩期血压平均在140mmHg以上,或舒张期血压在90mmHg以上,满足以上二者之一者作为高血压。根据血压的程度分为轻度高血压、中度高血压和重度高血压。轻度高血压是收缩压在140~150mmHg或舒张压在90 ~ 99mmHg者;中度高血压是收缩压在160 ~179mmHg或舒张压在100~109mmHg者;重度高血压是收缩压在180mmHg以上,或舒张压在110mmHg以上者。收缩压和舒张压属于不同的分类时,划入血压值高的一类。此外,舒张压在90mmHg以下,而收缩压在1 ……(未完,全文共15462字,当前仅显示2781字,请阅读下面提示信息。
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